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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
Q14008
USC-OGP 2-DE database
:
Q14008
Q14008
General information about the entry
View entry in simple text format
Entry name
CKAP5_HUMAN
Primary accession number
Q14008
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Cytoskeleton-associated protein 5; AltName: Full=Colonic and hepatic tumor overexpressed gene protein; Short=Ch-TOG;.
Gene name
Name=CKAP5
Synonyms=KIAA0097
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1148
:
pI=6.34; Mw=55360
Cross-references
UniProtKB/Swiss-Prot
Q14008; CKAP5_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
CKAP5_HUMAN
Primary accession number
Q14008
Secondary accession number(s)
Q05D70 Q0VAX7 Q0VAX8 Q14668 Q2TA89 Q6NSH4
Sequence was last modified on
November 4, 2008 (version 3)
Annotations were last modified on
March 15, 2017 (version 166)
Name and origin of the protein
Description
RecName: Full=Cytoskeleton-associated protein 5; AltName: Full=Colonic and hepatic tumor overexpressed gene protein; Short=Ch-TOG;
Gene name
Name=CKAP5
Synonyms=KIAA0097
Encoded on
Name=CKAP5; Synonyms=KIAA0097
Keywords
3D-structure
;
Acetylation
;
Alternative splicing
;
Cell cycle
;
Cell division
;
Centromere
;
Chromosome
;
Complete proteome
;
Cytoplasm
;
Cytoskeleton
;
Kinetochore
;
Mitosis
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
;
Repeat
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X92474; CAA63212.1
; -; mRNA
EMBL
D43948; BAA07892.2
; ALT_INIT; mRNA
EMBL
AC115088; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
BC017856; AAH17856.1
; ALT_SEQ; mRNA
EMBL
BC070136; AAH70136.1
; ALT_SEQ; mRNA
EMBL
BC111043; AAI11044.1
; ALT_SEQ; mRNA
EMBL
BC120869; AAI20870.1
; -; mRNA
EMBL
BC120870; AAI20871.1
; ALT_FRAME; mRNA
CCDS
CCDS31477.1; -. [Q14008-1]
; .
CCDS
CCDS7924.1; -. [Q14008-2]
; .
PIR
S68176; S68176
; .
RefSeq
NP_001008938.1; NM_001008938.3. [Q14008-1]
; .
RefSeq
NP_055571.2; NM_014756.3. [Q14008-2]
; .
UniGene
Hs.201253; -
; .
UniGene
Hs.737795; -
; .
PDB
4QMI; X-ray
; 1.90 A; A/B=846-1081
PDB
4QMJ; X-ray
; 2.50 A; A=846-1081
PDBsum
4QMI; -
; .
PDBsum
4QMJ; -
; .
ProteinModelPortal
Q14008; -
; .
SMR
Q14008; -
; .
BioGrid
115137; 97
; .
IntAct
Q14008; 65
; .
MINT
MINT-5002817; -
; .
STRING
9606.ENSP00000432768; -
; .
iPTMnet
Q14008; -
; .
PhosphoSitePlus
Q14008; -
; .
SwissPalm
Q14008; -
; .
BioMuta
CKAP5; -
; .
DMDM
212276513; -
; .
EPD
Q14008; -
; .
MaxQB
Q14008; -
; .
PaxDb
Q14008; -
; .
PeptideAtlas
Q14008; -
; .
PRIDE
Q14008; -
; .
Ensembl
ENST00000312055; ENSP00000310227
; ENSG00000175216. [Q14008-2]; .
Ensembl
ENST00000354558; ENSP00000346566
; ENSG00000175216. [Q14008-2]; .
Ensembl
ENST00000529230; ENSP00000432768
; ENSG00000175216. [Q14008-1]; .
GeneID
9793; -
; .
KEGG
hsa:9793; -
; .
UCSC
uc001ndi.3; human. [Q14008-1]
; .
CTD
9793; -
; .
DisGeNET
9793; -
; .
GeneCards
CKAP5; -
; .
H-InvDB
HIX0022364; -
; .
HGNC
HGNC:28959; CKAP5
; .
HPA
HPA039377; -
; .
HPA
HPA040375; -
; .
MIM
611142; gene
; .
neXtProt
NX_Q14008; -
; .
OpenTargets
ENSG00000175216; -
; .
PharmGKB
PA142672107; -
; .
eggNOG
KOG1820; Eukaryota
; .
eggNOG
ENOG410XPTW; LUCA
; .
GeneTree
ENSGT00390000014757; -
; .
HOVERGEN
HBG050955; -
; .
InParanoid
Q14008; -
; .
KO
K16803; -
; .
OMA
IFLPCLM; -
; .
OrthoDB
EOG091G00YR; -
; .
PhylomeDB
Q14008; -
; .
TreeFam
TF105639; -
; .
Reactome
R-HSA-2467813; Separation of Sister Chromatids
; .
Reactome
R-HSA-2500257; Resolution of Sister Chromatid Cohesion
; .
Reactome
R-HSA-2565942; Regulation of PLK1 Activity at G2/M Transition
; .
Reactome
R-HSA-380259; Loss of Nlp from mitotic centrosomes
; .
Reactome
R-HSA-380270; Recruitment of mitotic centrosome proteins and complexes
; .
Reactome
R-HSA-380284; Loss of proteins required for interphase microtubule organization from the centrosome
; .
Reactome
R-HSA-5620912; Anchoring of the basal body to the plasma membrane
; .
Reactome
R-HSA-5663220; RHO GTPases Activate Formins
; .
Reactome
R-HSA-68877; Mitotic Prometaphase
; .
Reactome
R-HSA-8854518; AURKA Activation by TPX2
; .
ChiTaRS
CKAP5; human
; .
GeneWiki
CKAP5; -
; .
GenomeRNAi
9793; -
; .
PRO
PR:Q14008; -
; .
Proteomes
UP000005640; Chromosome 11
; .
Bgee
ENSG00000175216; -
; .
CleanEx
HS_CKAP5; -
; .
ExpressionAtlas
Q14008; baseline and differential
; .
Genevisible
Q14008; HS
; .
GO
GO:0005813; C:centrosome
; IDA:UniProtKB; .
GO
GO:0000777; C:condensed chromosome kinetochore
; IEA:UniProtKB-SubCell; .
GO
GO:0005829; C:cytosol
; TAS:Reactome; .
GO
GO:0000776; C:kinetochore
; IDA:UniProtKB; .
GO
GO:0016020; C:membrane
; IDA:UniProtKB; .
GO
GO:0043234; C:protein complex
; IDA:MGI; .
GO
GO:0000922; C:spindle pole
; IDA:UniProtKB; .
GO
GO:0045296; F:cadherin binding
; IDA:BHF-UCL; .
GO
GO:0051010; F:microtubule plus-end binding
; IBA:GO_Central; .
GO
GO:0051301; P:cell division
; IEA:UniProtKB-KW; .
GO
GO:0051298; P:centrosome duplication
; IBA:GO_Central; .
GO
GO:0051297; P:centrosome organization
; IMP:HGNC; .
GO
GO:0097711; P:ciliary basal body docking
; TAS:Reactome; .
GO
GO:0030951; P:establishment or maintenance of microtubule cytoskeleton polarity
; IMP:HGNC; .
GO
GO:0000086; P:G2/M transition of mitotic cell cycle
; TAS:Reactome; .
GO
GO:0046785; P:microtubule polymerization
; IBA:GO_Central; .
GO
GO:0007067; P:mitotic nuclear division
; IEA:UniProtKB-KW; .
GO
GO:0050658; P:RNA transport
; ISS:HGNC; .
GO
GO:0007062; P:sister chromatid cohesion
; TAS:Reactome; .
GO
GO:0007051; P:spindle organization
; IMP:UniProtKB; .
Gene3D
1.25.10.10; -
; 6; .
InterPro
IPR011989; ARM-like
; .
InterPro
IPR016024; ARM-type_fold
; .
InterPro
IPR024395; CLASP_N_dom
; .
InterPro
IPR021133; HEAT_type_2
; .
InterPro
IPR034085; TOG
; .
Pfam
PF12348; CLASP_N
; 3; .
SMART
SM01349; TOG
; 5; .
SUPFAM
SSF48371; SSF48371
; 10; .
PROSITE
PS50077; HEAT_REPEAT
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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